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Medium-chain triglycerides (MCT) + whey protein isolate (WPI) is a therapeutic nutritional combination used in medical foods and dietary supplements to address protein-energy malnutrition, muscle wasting, and metabolic disorders. MCTs are saturated fats with 6 to 12 carbon atoms that are rapidly absorbed and oxidized, serving as a ketogenic energy source that can improve mitochondrial function. Whey protein isolate is a highly purified protein source containing all essential amino acids, particularly leucine, which is a potent stimulator of the mTORC1 signaling pathway. This combination is clinically utilized to manage sarcopenia in the elderly, support growth in pediatric patients with malabsorption, and provide the fat-to-protein ratios necessary for ketogenic diet therapy in refractory epilepsy.
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