Drug intelligence / Profile preview

Meganatural-Az grapeseed extract

Development stage
Phase 2
Lead developer
Polyphenolics
Modality
Small Molecules
Administration
Oral
01

Overview

MegaNatural-Az grapeseed extract is a proprietary, standardized dietary supplement derived from the seeds of California grapes (Vitis vinifera). It is rich in polyphenolic compounds—primarily oligomeric proanthocyanidins—which are potent antioxidants. The product has been studied for its potential cardiovascular benefits (such as supporting healthy blood pressure and endothelial function) and cognitive health effects. Preclinical research suggests that it may inhibit the formation of complex amyloid structures in the brain, potentially offsetting cognitive decline associated with Alzheimer's disease by preventing amyloid aggregation[4][5]. Its primary mechanism involves antioxidant activity and modulation of oxidative stress pathways; it may also influence vascular relaxation through effects on nitric oxide signaling[3][9]. Developed using a patented water-based extraction process to ensure purity and high polyphenol content.

Brand names
Meganatural-Az
Other names
MegaNatural-AZ grape seed extractMegaNatural AZgrape seed extractVitis vinifera L. (as relevant to this specific product)
02

Targets

Aβ (Amyloid-beta peptides and aggregates)

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