Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
megestrol acetate + olanzapine
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Megestrol acetate + olanzapine is a combination therapy used primarily for the treatment of cancer-related anorexia (CRA) and weight loss in patients with advanced cancer. Megestrol acetate is a synthetic progesterone derivative that may work by affecting certain hormones to slow the growth of certain tissues and increase appetite. Olanzapine is an atypical antipsychotic that has shown effectiveness in stimulating appetite and reducing nausea. The combination has demonstrated superior efficacy compared to megestrol acetate alone in improving weight gain, appetite, nausea, and quality of life measures in patients with advanced cancer.
02
Targets
HTR2A (Serotonin receptor 5-HT2A)DRD3 (Dopamine receptor D3)HTR6 (5-hydroxytryptamine receptor 6)DRD2 (Dopamine D2 Receptor)HTR2C (5-hydroxytryptamine 2C receptor)PR (Progesterone receptor)
Beyond the preview
Go deeper on megestrol acetate + olanzapine.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on megestrol acetate + olanzapine.