Drug intelligence / Profile preview

meglumine sodium succinate

Development stage
Phase 3
Modality
Small Molecules
Administration
Intravenous
01

Overview

Meglumine sodium succinate is a pharmaceutical compound used primarily as the active ingredient in the intravenous solution Reamberin. It is indicated for the treatment of metabolic acidosis, acute intoxication (including poisoning from alcohol and toxic gases), liver disease, cardiovascular disorders, postoperative recovery, and conditions involving hypoxia or impaired cellular metabolism[1][5][8]. The drug acts by activating enzymes involved in the Krebs cycle to enhance glucose and fatty acid utilization at the cellular level. This helps restore acid-base balance, improve cellular metabolism, support liver function, reduce oxidative stress by combating free radicals, and aid detoxification processes[1][5]. Meglumine sodium succinate is typically administered intravenously under medical supervision.

Brand names
Reamberin
Other names
N-methylglucamine succinate sodiumN-methyl glucamine succinateReamberin
02

Targets

SDH (Mitochondrial electron transport chain complex II)

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