Drug intelligence / Profile preview

Megon

Development stage
Approved
Lead developer
Genspec Lifesciences
Modality
Small Molecules
Administration
Oral
01

Overview

Megon is an oral tablet containing 160mg of megestrol acetate, a synthetic progestin developed and marketed by Genspec Lifesciences. As a progestogen, it primarily acts as an agonist of the progesterone receptor, though it also exhibits some glucocorticoid receptor activity. Megon is indicated for the treatment of anorexia, cachexia, or significant unexplained weight loss in patients with advanced cancer or HIV/AIDS. Additionally, it is used as a palliative treatment for hormone-dependent malignancies, such as breast and endometrial carcinomas. The medication works by modulating the hormonal environment to slow cancer progression and by stimulating appetite through complex metabolic and neuroendocrine pathways.

Brand names
Megon
Other names
megestrol acetate
02

Targets

GR (Glucocorticoid receptor)PR (Progesterone receptor)

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