Drug intelligence / Profile preview

Meitoxin

Development stage
Unknown
Lead developer
Zhuyangxin Pharmaceutical
Modality
Small Molecules
Administration
Topical
01

Overview

Meitoxin (美多信) is a topical antibiotic ointment containing mupirocin, developed by Hangzhou Zhuyangxin Pharmaceutical. It acts by specifically and reversibly binding to bacterial isoleucyl-tRNA synthetase, which inhibits the incorporation of isoleucine into bacterial proteins, thereby halting protein synthesis. This unique mechanism of action is distinct from other antibiotic classes, which helps minimize cross-resistance. Meitoxin is primarily indicated for the treatment of primary and secondary skin infections caused by susceptible gram-positive bacteria, including *Staphylococcus aureus* (including methicillin-resistant strains/MRSA) and *Streptococcus pyogenes*. Common clinical applications include the treatment of impetigo, folliculitis, boils, and secondary infections associated with eczema or minor traumatic wounds.

Brand names
Meitoxin美多信
Other names
mupirocin莫匹罗星Mupirocin Ointment莫匹罗星软膏
02

Targets

IleRS (Isoleucyl-tRNA synthetase)

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