Drug intelligence / Profile preview

MEL-P15

Development stage
Preclinical
Lead developer
Cerapedics
Modality
Peptides
01

Overview

MEL-P15 is a peptide derived from **melittin**, which is the main toxic component in the venom of the European honeybee (Apis mellifera). MEL-P15 has been specifically studied for its **anti-hepatocellular carcinoma activity**, demonstrating cytotoxic effects against liver cancer cells. The mechanism of action is related to its peptide structure, which influences cell membrane permeability and induces cell death in cancer cells. Its activity is distinct from native melittin in terms of selectivity and toxicity profile[3].

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