Drug intelligence / Profile preview

Melanotan II

Development stage
Phase 2
Lead developer
University of Arizona
Modality
Peptides
Administration
Subcutaneous, Intranasal
01

Overview

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH). It stimulates melanogenesis to facilitate tanning and may increase sexual arousal. It is used for sunless tanning, appetite suppression, and inducing sexual desire and penile erection. However, it is not approved for any medical conditions and has serious safety concerns, including potential links to melanoma and other side effects like nausea and facial flushing.

Other names
MT-II
02

Targets

MC4R (Melanocortin 4 receptor)MC3R (Melanocortin Receptor Type 3)MC1R (Melanocortin Type 1 Receptor)MC5R (Melanocortin 5 Receptor)

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