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melatonin + peppermint oil + simethicone
- Development stage
- Phase 1
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination of three active ingredients used for gastrointestinal issues. **Melatonin** has analgesic effects which may help alleviate abdominal pain and influence the sensation of abdominal distention in IBS patients. **Peppermint oil** helps to relax smooth muscle and breaks up gas, making it easier to release. **Simethicone** relieves painful pressure from excess gas and bloating in the stomach and intestines by breaking up gas bubbles in the gut.
02
Targets
MTNR1A (MT1)MTNR1B (Melatonin Receptor 2)
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