Drug intelligence / Profile preview

Melaxin

Development stage
Discontinued
Modality
Cell Therapies, Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

Melaxin is an autologous cellular vaccine developed for the treatment of malignant melanoma. It functions as an immunotherapy by creating "dendritomas," which are hybrid fusion cells formed by combining a patient's own tumor cells with their dendritic cells. These dendritomas are designed to present the full repertoire of tumor antigens to the immune system, thereby stimulating an anti-tumor immune response. In clinical trials, Melaxin has been investigated for its efficacy in Stage IV malignant melanoma, administered subcutaneously in combination with Bacillus Calmette-Guerin (BCG) injections.

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