Drug intelligence / Profile preview

Melilotus officinalis pollen

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Melilotus officinalis pollen is derived from the plant commonly known as yellow sweetclover or sweet clover, a species of legume native to Eurasia. Traditionally, extracts from *Melilotus officinalis* (including parts of the flowering plant) have been used for their medicinal properties, particularly in treating venous circulation disorders, edema, hemorrhoids, and varicose veins. The plant contains active compounds such as coumarins (which can convert to dicoumarol, a potent anticoagulant), flavonoids, and phenolic acids. These constituents contribute to its reported anti-inflammatory, antiedematous, and antioxidant effects. While the pollen itself is also recognized as a mild allergen, the plant's extracts are utilized in various herbal remedies and dietary supplements for their purported benefits in improving lymphatic function, increasing venous return, and acting as a mild anticoagulant.

Other names
Yellow Sweetclover pollenSweet Clover pollenYellow Melilot pollenRibbed Melilot pollenCommon Melilot pollen
02

Targets

NOS2 (Nitric Oxide Synthase 2)VKORC1 (Vitamin K epoxide reductase complex subunit 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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