Drug intelligence / Profile preview

melissa officinalis

Development stage
Phase 3
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Melissa officinalis, commonly known as lemon balm, is a perennial herb in the mint family (Lamiaceae) native to Europe and the Mediterranean region but now grown worldwide. The leaves are used medicinally and contain volatile oils (citral, citronellal), polyphenols (rosmarinic acid), flavonoids, tannins, and other phytochemicals. Lemon balm has traditionally been used for its calming effects on the nervous system—helping with anxiety, stress-related symptoms, insomnia—as well as for digestive complaints such as indigestion and bloating. It also exhibits antiviral activity against herpes simplex virus when applied topically and may have mild antibacterial and antifungal properties. Some studies suggest benefits for cognitive function (including in dementia/Alzheimer’s disease), mood elevation in depression or anxiety states, relief of PMS symptoms, antispasmodic effects on smooth muscle (gastrointestinal tract), cardiotonic actions supporting heart health by reducing palpitations or blood pressure modestly in some cases. Its mechanism of action is thought to involve modulation of GABAergic neurotransmission via muscarinic/nicotinic acetylcholine receptors; inhibition of viral replication; antioxidant activity; anti-inflammatory pathways; possible thyroid hormone antagonism by inhibiting TSH receptor binding.

Other names
lemon balmbalmlemon balmsmelissa officinalibee balm
02

Targets

GABRR (GABA-A receptor subunit rho)HSV DNA pol (Herpes simplex virus DNA polymerase)ABAT (4-aminobutyrate aminotransferase)

Beyond the preview

Go deeper on melissa officinalis.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on melissa officinalis.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call