Drug intelligence / Profile preview

Men-B-Bio

Development stage: Unknown
Lead developer: Immunobiological Technology Institute (Bio-Manguinhos), Oswaldo Cruz Foundation (Fiocruz)
Modality: Vaccines & Immunotherapeutics
Administration: Intramuscular

Overview

Men-B-Bio is an investigational meningococcal serogroup B vaccine developed by Bio-Manguinhos/Fiocruz in collaboration with Instituto Butantan and the Adolfo Lutz Institute in Brazil. The vaccine is composed of detergent-treated outer membrane vesicles (OMVs) and detoxified lipooligosaccharide (dLOS) derived from prevalent Brazilian strains of Neisseria meningitidis serogroup B. It is designed to elicit a protective antibody response against serogroup B surface antigens. Clinical evaluation has included a randomized Phase II/III trial in children aged 4–11 years to assess immunogenicity and safety compared to the Cuban vaccine VAMENGOC-BC.

Other names: Brazilian MenB vaccineMeningococcus B Brazilian vaccine

Targets

fHbp (Factor H-binding protein)NadA (Neisserial adhesin A)Neisseria meningitidis serogroup B outer membrane vesicle surface epitopesNHBA (Neisserial heparin-binding antigen)

Beyond the preview

Go deeper on Men-B-Bio.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Men-B-Bio.

Explore the full profile