Drug intelligence / Profile preview

Menactra

Development stage
Approved
Lead developer
Sanofi Pasteur
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Menactra is a quadrivalent meningococcal conjugate vaccine developed by Sanofi for active immunization against invasive disease caused by *Neisseria meningitidis* serogroups A, C, Y, and W-135. Each 0.5 mL intramuscular dose contains 4 mcg of each serogroup-specific capsular polysaccharide conjugated to approximately 48 mcg total diphtheria toxoid carrier protein. The conjugate design elicits functional bactericidal antibodies and immunologic memory against the included meningococcal serogroups; it does not protect against serogroup B disease. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4d8781ff-9366-462c-8161-6e958f44fcb4))

Brand names
Menactra
Other names
MenACWY-DMeningococcal groups A, C, Y and W-135 polysaccharide diphtheria toxoid conjugate vaccineTetraMenD
02

Targets

Neisseria meningitidis group C capsular polysaccharideMenW CPS (Neisseria meningitidis serogroup W capsular polysaccharide)NmA CPS (Neisseria meningitidis group A capsular polysaccharide)Group Y CPS (Neisseria meningitidis group Y capsular polysaccharide)

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