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Menactra is a quadrivalent meningococcal conjugate vaccine developed by Sanofi for active immunization against invasive disease caused by *Neisseria meningitidis* serogroups A, C, Y, and W-135. Each 0.5 mL intramuscular dose contains 4 mcg of each serogroup-specific capsular polysaccharide conjugated to approximately 48 mcg total diphtheria toxoid carrier protein. The conjugate design elicits functional bactericidal antibodies and immunologic memory against the included meningococcal serogroups; it does not protect against serogroup B disease. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4d8781ff-9366-462c-8161-6e958f44fcb4))
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