Drug intelligence / Profile preview

MenBvac

Development stage
Phase 4
Lead developer
Norwegian Institute of Public Health
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

MenBvac is an outer membrane vesicle vaccine developed to prevent systemic meningococcal disease caused by serogroup B Neisseria meningitidis. Clinical studies have demonstrated that a four-dose regimen (three primary doses 6 weeks apart followed by a fourth booster dose a year later) provides good immunogenicity with prolonged persistence and increased cross-reactivity of functional antibodies. The vaccine has shown an acceptable safety profile with mild to moderate local and systemic reactions.

Brand names
MenBvac
Other names
MenBVac vaccineOuter membrane vesicle meningococcal B vaccineOMV-based meningococcal B vaccine
02

Targets

Neisseria meningitidis serogroup B outer membrane antigens

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