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MenC-CRM197 conjugate vaccine

Development stage
Unknown
Lead developer
Novartis
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

MenC-CRM197 conjugate vaccine is a monovalent vaccine designed for the prevention of invasive disease caused by *Neisseria meningitidis* serogroup C. It consists of polysaccharide from the C serogroup of *Neisseria meningitidis* chemically conjugated to CRM197, which is a genetically detoxified variant of diphtheria toxin. The conjugation to CRM197 enhances immunogenicity by eliciting a T cell-dependent immune response, including immune memory, particularly in infants and young children, populations that respond poorly to plain polysaccharide vaccines. The primary indication is prevention of meningococcal group C disease.

Brand names
MeningitecMenjugate
Other names
Meningococcal C-CRM197 conjugate vaccineMenC-CRMMenC-CRM197MenC-CRM-197MenC-CRM 197
02

Targets

Neisseria meningitidis group C capsular polysaccharide

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