Drug intelligence / Profile preview

Menhycia

Development stage
Unknown
Lead developer
CanSino Biologics
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Menhycia is a quadrivalent meningococcal conjugate vaccine developed by CanSino Biologics for the prevention of epidemic cerebrospinal meningitis. The vaccine is composed of purified capsular polysaccharides from four serogroups of *Neisseria meningitidis* (A, C, Y, and W135), each covalently conjugated to the CRM197 carrier protein, a non-toxic mutant of the diphtheria toxin. This conjugation converts the T-cell independent polysaccharide antigens into T-cell dependent antigens, significantly improving immunogenicity and inducing immunological memory, particularly in infants and young children. Menhycia is indicated for active immunization in children aged 3 months to 6 years (83 months) and was the first quadrivalent meningococcal conjugate vaccine to be approved in China.

Brand names
Menhycia
Other names
Group ACYW135 Meningococcal Polysaccharide Conjugate Vaccine (CRM197)ACYW135 Meningococcal Conjugate VaccineACYW-135 Meningococcal Conjugate VaccineACYW 135 Meningococcal Conjugate VaccineMenACYW-CRM197MenACYW-CRM-197MenACYW-CRM 197CanSino MCV4
02

Targets

NmA CPS (Neisseria meningitidis group A capsular polysaccharide)Neisseria meningitidis group C capsular polysaccharideMenW CPS (Neisseria meningitidis serogroup W capsular polysaccharide)Group Y CPS (Neisseria meningitidis group Y capsular polysaccharide)

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