Drug intelligence / Profile preview

meningococcal (group A, C, Y, W135) polysaccharide conjugate vaccine

Development stage
Unknown
Lead developer
CanSino Biologics
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The meningococcal (group A, C, Y, W135) polysaccharide conjugate vaccine is a quadrivalent vaccine designed to provide active immunization against invasive meningococcal disease caused by *Neisseria meningitidis* serogroups A, C, Y, and W135. Developed by Beijing Green Bamboo Biological Pharmacy, this specific conjugate vaccine candidate utilizes capsular polysaccharides from the four serogroups chemically linked to a carrier protein (such as tetanus toxoid). This conjugation process enhances the immune response by engaging T-cells, which is particularly critical for inducing effective and lasting immunity in infants and young children, a population where plain polysaccharide vaccines are often poorly immunogenic. The vaccine is currently undergoing Phase 3 clinical evaluation in China to assess its safety, immunogenicity, and immune persistence in healthy infants and children aged 6 months to 5 years.

Other names
ACYW135 meningococcal conjugate vaccineACYW-135 meningococcal conjugate vaccineACYW 135 meningococcal conjugate vaccineQuadrivalent meningococcal conjugate vaccine
02

Targets

Neisseria meningitidis group C capsular polysaccharideNmA CPS (Neisseria meningitidis group A capsular polysaccharide)MenW CPS (Neisseria meningitidis serogroup W capsular polysaccharide)Group Y CPS (Neisseria meningitidis group Y capsular polysaccharide)

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