meningococcal ACYW135 vaccine

The meningococcal ACYW135 vaccine is a quadrivalent bacterial vaccine designed to protect against invasive disease caused by *Neisseria meningitidis* serogroups A, C, W-135 (also called W), and Y. It is available in both conjugate and polysaccharide formulations. The conjugate vaccines (such as those using diphtheria toxoid or CRM197 as carrier proteins) induce a T-cell dependent immune response that provides longer-lasting immunity and immunologic memory compared to the older polysaccharide vaccines. The primary indication for this vaccine is the prevention of serious illnesses such as bacterial meningitis and septicemia caused by these four serogroups of *Neisseria meningitidis*. It is recommended for routine use in adolescents and certain high-risk groups including people with specific medical conditions affecting the immune system (e.g., complement deficiencies or asplenia), travelers to endemic regions (such as parts of Africa), college students living in dormitories who have not been previously vaccinated, military recruits, microbiologists working with *N. meningitidis* isolates, and during outbreaks[1][2][3][4][5]. Multiple manufacturers produce different brands globally.

Brand names

MenveoMenQuadfiMenactraNimenrixMencevax ACWY

Other names

MenACWY vaccinequadrivalent meningococcal conjugate vaccinequadrivalent meningococcal polysaccharide vaccineMenC-ACYW vaccine