Drug intelligence / Profile preview

meningococcal conjugate vaccine ACWY

Development stage
Approved
Lead developer
Sanofi Pasteur
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The **meningococcal conjugate vaccine ACWY** is a quadrivalent bacterial vaccine indicated for active immunization to prevent invasive meningococcal disease caused by *Neisseria meningitidis* serogroups A, C, W, and Y in children and adults. It works by inducing the body's immune system to produce antibodies against these serogroups, preventing serious infections like bacterial meningitis and sepsis. The vaccine contains purified capsular polysaccharides from each target group conjugated to a carrier protein (such as diphtheria or tetanus toxoid), enhancing immunogenicity. It does **not** protect against serogroup B and does not treat active infection. Its primary indications include routine immunization in adolescents, as well as use for people at increased risk (e.g., those with certain medical conditions, travelers to endemic regions, military recruits, and college freshmen in group housing)[1][2][3][4][6].

Brand names
MenactraMenveoMenQuadfi
Other names
meningococcal (groups A, C, Y, W) conjugate vaccineMenACWYquadrivalent meningococcal conjugate vaccine
02

Targets

Neisseria meningitidis group C capsular polysaccharideMenW CPS (Neisseria meningitidis serogroup W capsular polysaccharide)Group Y CPS (Neisseria meningitidis group Y capsular polysaccharide)NmA CPS (Neisseria meningitidis group A capsular polysaccharide)

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