Drug intelligence / Profile preview

meningococcal group A, C, W-135 and Y conjugate vaccine + measles, mumps, rubella and varicella vaccine (live)

Development stage
Unknown
Lead developer
GSK
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular, Subcutaneous
01

Overview

Nimenrix + Priorix-Tetra refers to the concomitant administration of two separate vaccines developed by GSK. **Nimenrix** is a quadrivalent meningococcal conjugate vaccine (MenACWY-TT) that uses tetanus toxoid as a carrier protein and is indicated for the prevention of invasive meningococcal disease caused by *Neisseria meningitidis* serogroups A, C, W-135, and Y. **Priorix-Tetra** is a live attenuated vaccine containing measles, mumps, rubella, and varicella (MMRV) antigens. These biologics are typically administered together during the second year of life (12–15 months) to simplify pediatric vaccination schedules. Clinical trials have demonstrated that co-administration at different injection sites is safe and does not significantly interfere with the immunogenicity or safety profile of either vaccine, ensuring protective antibody levels against all eight targeted pathogens.

Other names
MenACWY-TT + MMRVMeMuRu-OKA + MenACWY-TTMMRV-Oka + MenACWY-TT
02

Targets

NmA CPS (Neisseria meningitidis group A capsular polysaccharide)Group Y CPS (Neisseria meningitidis group Y capsular polysaccharide)Mumps virus antigenNeisseria meningitidis group C capsular polysaccharideMenW CPS (Neisseria meningitidis serogroup W capsular polysaccharide)TT (Tetanus toxoid)MV (Measles virus)

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