Drug intelligence / Profile preview

meningococcal group A, C, Y and W135 conjugate vaccine (Juwei Biotech)

Development stage
Unknown
Lead developer
Suzhou Ju Microbial Technology
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

ACYW135群脑膜炎球菌结合疫苗 (MCV-4) is a quadrivalent polysaccharide conjugate vaccine developed by **Suzhou Juwei Biological Technology** (苏州聚微生物科技). The vaccine is designed to prevent invasive meningococcal disease caused by *Neisseria meningitidis* serogroups A, C, Y, and W135. Unlike plain polysaccharide vaccines, this conjugate formulation chemically links the capsular polysaccharides of the four serogroups to a carrier protein, which enhances the immune response by engaging T-cells. This mechanism is particularly critical for inducing long-term immunological memory and providing protection in infants and young children. The drug is currently in **Phase 3** clinical trials in China, targeting a broad age range from infants to adults.

Other names
ACYW135群脑膜炎球菌结合疫苗冻干ACYW135群脑膜炎球菌结合疫苗Quadrivalent Meningococcal Conjugate VaccineACYW135 Meningococcal Polysaccharide Conjugate VaccineACYW-135 Meningococcal Polysaccharide Conjugate VaccineACYW 135 Meningococcal Polysaccharide Conjugate Vaccine
02

Targets

Neisseria meningitidis group C capsular polysaccharideGroup Y CPS (Neisseria meningitidis group Y capsular polysaccharide)MenW CPS (Neisseria meningitidis serogroup W capsular polysaccharide)NmA CPS (Neisseria meningitidis group A capsular polysaccharide)

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