Drug intelligence / Profile preview

Meningococcal group A and C conjugate vaccine (Walvax Biotechnology Co., Ltd.)

Development stage
Unknown
Lead developer
Walvax Biotechnology
Modality
Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The meningococcal group A and C conjugate vaccine is a bivalent vaccine developed and manufactured by Yuxi Walvax Biotechnology Co., Ltd. for the prevention of invasive meningococcal disease caused by *Neisseria meningitidis* serogroups A and C. The vaccine consists of purified capsular polysaccharides from serogroups A and C, each covalently linked to a tetanus toxoid carrier protein. This conjugation enhances the immune response by recruiting T-cell help, which is essential for inducing high-affinity antibodies and immunological memory, particularly in infants whose immune systems respond poorly to plain polysaccharide vaccines. Administered via intramuscular injection, the vaccine is approved in China for use in children aged 3 months to 5 years, with dosing schedules varying by age. Clinical and post-marketing data have demonstrated a favorable safety profile and robust immunogenicity in the pediatric population.

Other names
Group A and C meningococcal polysaccharide conjugate vaccineAC conjugate vaccineMeningococcal group A and C polysaccharide conjugate vaccine (tetanus toxoid)
02

Targets

Neisseria meningitidis group C capsular polysaccharideNmA CPS (Neisseria meningitidis group A capsular polysaccharide)

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