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meningococcal group c polysaccharide-tetanus toxoid conjugate vaccine
- Development stage
- Phase 2
- Lead developer
- Pfizer
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Meningococcal group C polysaccharide-tetanus toxoid conjugate vaccine is a monovalent conjugate vaccine designed to prevent invasive disease caused by *Neisseria meningitidis* serogroup C. The active component is de-O-acetylated group C meningococcal polysaccharide covalently linked to tetanus toxoid protein, which acts as a carrier and enhances immunogenicity. This formulation induces robust antibody responses and long-lasting immunity in infants, children, and adults by stimulating T-cell dependent immune mechanisms. It has been shown to be highly effective in reducing the incidence of serogroup C disease following mass vaccination campaigns[3][4][5]. The primary indication is prevention of invasive meningococcal disease (meningitis and septicemia) due to serogroup C.
- Brand names
- NeisVac-C
- Other names
- meningococcal group C conjugate vaccineMenC-TTGCMP-TT
02
Targets
Neisseria meningitidis group C capsular polysaccharideTT (Tetanus toxoid)
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