Drug intelligence / Profile preview

meningococcal polysaccharide vaccine serogroup A + meningococcal polysaccharide vaccine serogroup C

Development stage
Unknown
Lead developer
Walvax Biotechnology
Modality
Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

A combination vaccine composed of purified capsular polysaccharides from *Neisseria meningitidis* serogroups A and C. The vaccine stimulates the immune system to produce antibodies against the bacterial polysaccharide capsules, providing immunity to invasive meningococcal disease caused by serogroups A and C. Unlike conjugate vaccines, pure polysaccharide vaccines elicit a T cell-independent immune response, resulting in short-lived antibody titers and no immunological memory, particularly in young children. Typical indications are rapid protection in high-risk populations, outbreak response, and use where conjugate vaccines are unavailable or inappropriate. The vaccine is not effective against other meningococcal serogroups and does not induce herd immunity[4].

Other names
meningococcal polysaccharide vaccine A/Cgroup A and C meningococcal polysaccharide vaccineNeisseria meningitidis group A and C capsular polysaccharide vaccine
02

Targets

NmA CPS (Neisseria meningitidis group A capsular polysaccharide)Neisseria meningitidis group C capsular polysaccharide

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