Drug intelligence / Profile preview

meningococcal vaccine (VBC)

Development stage
Unknown
Lead developer
Finlay Vaccine Institute
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular, Subcutaneous
01

Overview

The meningitis vaccine developed by VBC (Vietnam Biopharmaceutical Corporation) is a biological preparation designed to provide active immunization against *Neisseria meningitidis*, the primary causative agent of meningococcal meningitis. VBC's portfolio includes the Meningo AC vaccine, a bivalent polysaccharide vaccine targeting serogroups A and C, and the Meningo BC vaccine, which targets serogroups B and C. The Meningo BC formulation is particularly significant as it utilizes outer membrane proteins to elicit an immune response against serogroup B, which is not effectively addressed by traditional polysaccharide-only vaccines. These vaccines work by stimulating the host's immune system to produce protective bactericidal antibodies that recognize and neutralize the bacteria, thereby preventing invasive disease and its severe complications such as septicemia and permanent neurological damage.

Brand names
Meningo ACMeningo BC
Other names
VBC meningitis vaccinemeningococcal polysaccharide vaccine (VBC)
02

Targets

Neisseria meningitidis group C capsular polysaccharideMenB OMV (Neisseria meningitidis serogroup B outer membrane vesicle)

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