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Drug intelligence / Profile preview
menotrophin
- Development stage
- Phase 4
- Lead developer
- Ferring Pharmaceuticals
- Administration
- Intramuscular, Subcutaneous
01
Overview
**Menotrophin** is a urine-derived human menopausal gonadotropin preparation used to stimulate follicular development and ovulation in infertility treatment, including controlled ovarian stimulation for assisted reproductive technology. It contains follicle-stimulating hormone and luteinizing hormone bioactivity obtained from the urine of postmenopausal women. By activating follicle-stimulating hormone receptors and luteinizing hormone/choriogonadotropin receptors in the ovary, it promotes follicular growth, steroidogenesis, oocyte maturation, and ovulation. Commercial preparations include highly purified injectable products such as Menopur. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=22c8db95-c3db-1770-8086-31356fbabe35))
- Brand names
- MenopurRepronex
- Other names
- menotropinmenotropinshuman menopausal gonadotrophinhuman menopausal gonadotropinhMG
02
Targets
FSHR (Follicle-stimulating hormone receptor)LHCGR (Luteinizing hormone/choriogonadotropin receptor)
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