Drug intelligence / Profile preview

menotropins

Development stage
Approved
Lead developer
Ferring Pharmaceuticals
Modality
Recombinant Proteins and Enzymes
Administration
Subcutaneous, Intramuscular
01

Overview

Menotropins is a purified combination of human follicle-stimulating hormone (FSH) and luteinizing hormone (LH), both extracted from the urine of postmenopausal women. It is used as a fertility medication to stimulate ovarian follicular growth and development in women undergoing assisted reproductive technology (ART) procedures such as in vitro fertilization (IVF). The drug acts by binding to the follicle-stimulating hormone receptor and luteinizing hormone receptor on ovarian cells. FSH promotes recruitment and growth of ovarian follicles during early folliculogenesis while LH supports steroidogenesis and maturation of pre-ovulatory follicles. Menotropins are administered via subcutaneous or intramuscular injection[2][3][7].

Brand names
MenopurPergonalHumegonRepronexMenodacIVF MHMG -SP 75NugonGonotrop -FManodac
Other names
human menopausal gonadotropin
02

Targets

FSHR (Follicle-stimulating hormone receptor)LHCGR (Luteinizing hormone/choriogonadotropin receptor)

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