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Mensospas
- Development stage
- Unknown
- Lead developer
- Anthus Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Mensospas is an oral combination tablet developed and marketed by Anthus Pharmaceuticals for the treatment of spasm-related pain and dysmenorrhea (menstrual cramps). The formulation contains three active ingredients: mefenamic acid (500mg), pamabrom (25mg), and dicyclomine hydrochloride (10mg). Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that provides analgesic and anti-inflammatory effects by inhibiting prostaglandin synthesis. Dicyclomine hydrochloride is an antispasmodic agent that relieves smooth muscle spasms in the gastrointestinal and urogenital tracts by antagonizing muscarinic receptors. Pamabrom is a mild diuretic that helps alleviate water retention and bloating associated with menstruation. This multi-modal approach is designed to address the primary symptoms of dysmenorrhea, including pain, cramping, and bloating. The drug is approved and marketed in India as a prescription product.
- Brand names
- Mensospas
02
Targets
ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)M1 (Muscarinic acetylcholine receptor M1)CHRM3 (M3)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ADOR (Adenosine receptors)
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