Drug intelligence / Profile preview

mentha suaveolens extract

Development stage
Preclinical
Lead developer
Biospectrum Life Science Institute
Administration
Oral, Topical
01

Overview

Mentha suaveolens extract is a natural preparation derived from the leaves of Mentha suaveolens, commonly known as apple mint. This extract is typically produced using aqueous, steam, or alcohol extraction methods from dried and crushed leaves. It exhibits a range of biological activities including **antimicrobial, antioxidant, anti-inflammatory, cytoprotective**, and **hepatoprotective** effects[1][3][5]. Mechanistically, it acts partly through the activation of Nrf2-mediated phase II enzyme expression (notably heme oxygenase-1/HO-1), reducing oxidative stress-induced apoptosis in human keratinocyte cells[1]. Additionally, it displays antibacterial effects, helps regulate oil secretions in skin, reduces irritation and redness, and offers nourishing and refreshing properties in cosmetic use[3]. Apple mint extract is employed in traditional medicine for gastrointestinal problems, respiratory symptoms, and as an analgesic and antidiarrheal agent[5].

Other names
mentha suaveolens leaf extractapple mint extractMSAEapple mint leaf extract
02

Targets

HMOX1 (Heme oxygenase 1)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)

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