Drug intelligence / Profile preview

menthol + camphor + cineol

Development stage
Phase 3
Modality
Small Molecules
Administration
Topical, Inhalation
01

Overview

This is a combination of three aromatic compounds—menthol, camphor, and cineol (also known as eucalyptol or 1,8-cineole)—commonly used in topical preparations and inhalants for the symptomatic relief of respiratory conditions such as cough, nasal congestion, sinusitis, allergic rhinitis, and minor throat irritation. - **Menthol** is derived from mint oils and acts by activating cold-sensitive receptors in the skin and mucosa to produce a cooling sensation. It has mild local anesthetic properties that help relieve pain and irritation while also acting as a decongestant by opening nasal passages[3][4][6]. - **Camphor** is obtained from the wood of the Cinnamomum camphora tree. It provides both cooling and warming sensations when applied topically or inhaled. Camphor acts as a mild analgesic (pain reliever), decongestant (relieves stuffy nose), counterirritant (distracts from deeper pain), anti-inflammatory agent, and has some antimicrobial activity[4]. - **Cineol** (eucalyptol/1,8-cineole) is found in eucalyptus oil. It exhibits mucolytic effects (helps break down mucus), anti-inflammatory action by inhibiting pro-inflammatory cytokines such as IL-1β and IL-6[2], expectorant properties to clear airways[5], antimicrobial activity against certain pathogens[2], and can reduce airway inflammation. The combination works through sensory stimulation of nerve endings in the skin/mucosa to provide rapid relief from symptoms via aromatherapy effects when inhaled or topical application on chest/throat/back areas. The main indications are temporary relief of coughs due to colds/flu/allergies; easing breathing; soothing sore throat; reducing chest/nasal discomfort; relieving minor aches/pains associated with upper respiratory tract infections.

Brand names
Transpulmin
Other names
menthol + camphor + eucalyptolmenthol + camphor + 1,8-cineole
02

Targets

TRPA1 (Transient receptor potential cation channel subfamily A member 1)TRPV1 (Transient receptor potential cation channel subfamily V member 1)TRPV3 (Transient receptor potential vanilloid subtype 3)

Beyond the preview

Go deeper on menthol + camphor + cineol.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on menthol + camphor + cineol.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call