menthol + capsaicin

**Menthol + capsaicin** is a topical combination medication used for symptomatic relief of **minor aches and pains in muscles and joints**, including those caused by arthritis, backache, sprains, bruises, diabetic nerve pain, and strains[2][5]. It is available over-the-counter (OTC) as a cream, gel, or patch. **Capsaicin** is derived from chili peppers and acts as a counterirritant by activating skin sensory receptors, reducing their sensitivity to other pain signals. **Menthol** is a natural chemical from peppermint that also acts as a counterirritant, initially cooling and then warming the skin, which distracts from pain perception[2][5]. The medication is generally well tolerated with few side effects, though it can cause a burning sensation and local irritation, especially if applied to damaged skin or sensitive areas[2][5].

Brand names

Capzasin Quick ReliefZostrix Diabetic Pain ReliefZostrix Hot & Cold TherapySalonpas Pain Relieving Gel-Patch HotInstaSoothe Pain Relief Cream

Other names

capsaicin/mentholcapsaicin and menthol cream and gel