Drug intelligence / Profile preview

Mentholatum Original Ointment

Development stage
Unknown
Lead developer
Rohto Pharmaceutical
Modality
Small Molecules
Administration
Topical
01

Overview

Mentholatum is a line of over-the-counter (OTC) topical vapor rubs and ointments developed by The Mentholatum Company, a subsidiary of Rohto Pharmaceutical. These products are primarily used for the symptomatic relief of cough and cold symptoms, including chest and nasal congestion, as well as minor muscle aches. The formulations typically contain a combination of natural active ingredients such as camphor (9%) and menthol (1.3%), which act as counterirritants. When applied topically to the chest, throat, or back, the product releases aromatic vapors that soothe nasal passages and provide a cooling sensation, while the topical application helps alleviate minor aches and pains through counterirritant mechanisms. The brand has been commercially available since 1889 and is approved for use in adults and children aged 2 and older.

Brand names
Mentholatum Original OintmentMentholatum Nighttime Vaporizing RubMentholatum Vapor-MaxMentholatum
Other names
Mentholatum rubMentholatum vapor rub
02

Targets

TRPM8 (Transient receptor potential cation channel subfamily M member 8)TRPV1 (Transient receptor potential cation channel subfamily V member 1)TRPA1 (Transient receptor potential cation channel subfamily A member 1)

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