Drug intelligence / Profile preview

meperizumab

Development stage
Phase 1
Lead developer
Chia Tai-Tianqing Pharmaceutical Group
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Subcutaneous, Parenteral
01

Overview

**Meperizumab** is a proposed monoclonal antibody biosimilar to **mepolizumab** referencing **Nucala**. Publicly verifiable evidence from a registered Phase 1 study shows it was developed by **Chia Tai Tianqing Pharmaceutical Group** for pharmacokinetic and safety similarity testing versus Nucala in healthy male volunteers. Based on its reference product, meperizumab is intended to act as an **interleukin-5 neutralizing antibody**, thereby reducing eosinophilic inflammation; however, the public evidence located here is centered on biosimilarity evaluation rather than a detailed independent nonclinical or clinical mechanism package for meperizumab itself.

Other names
meperizumabMeperizumab injection
02

Targets

IL-5 (Interleukin 5)

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