mepivacaine

Mepivacaine is an amide-type local anesthetic used for local or regional analgesia or anesthesia. It is chemically related to bupivacaine and pharmacologically similar to lidocaine. Mepivacaine works by stabilizing the neuronal membrane and blocking sodium channels on the intracellular surface of nerve cells. This action prevents the initiation and transmission of nerve impulses required for pain sensation[2][5][8]. It is indicated for infiltration anesthesia (injection into tissue), nerve block (injection near nerves), epidural anesthesia (injection into the epidural space), and dental procedures in both adults and pediatric patients[1][4][5]. Mepivacaine is rapidly metabolized in the liver with a half-life of 1.9–3.2 hours in adults[2][5]. Systemic absorption can affect both cardiovascular and central nervous systems at high concentrations[6].

Brand names

CarbocaineCarbocaine With NeocobefrinIsocaineIsocaine With LevonordefrinPolocaineScandonestScandonest LScandonest PlainPolocaine DENTALPolocaine-MPFCarbocaine HCl

Other names

mepivacaine hydrochloride