Drug intelligence / Profile preview

mepuzapine

Development stage
Unknown
Lead developer
Venturepharm
Modality
Small Molecules
Administration
Oral
01

Overview

Mepuzapine (VPC-14) is a novel small molecule analgesic developed by Beijing Dezhong Wanquan Pharmaceutical Technology (Venturepharm). Chemically a dibenzo[b,e][1,4]diazepine derivative, it is being investigated as a centrally acting, non-opioid treatment for moderate to acute pain. The drug is designed to offer potent analgesia without the addiction liability or respiratory depression typically associated with opioid medications. Clinical development has primarily occurred in China, where it has undergone Phase 1 pharmacokinetic evaluation in healthy volunteers to characterize its plasma concentration–time profile and safety.

Other names
mepuzapine hydrochloride美普扎平

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