Drug intelligence / Profile preview

Mercapton

Development stage
Unknown
Lead developer
Medi-Radiopharma
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

Mercapton is a diagnostic radiopharmaceutical cold kit developed by Medi-Radiopharma for renal cortical imaging. The kit contains dimercaptosuccinic acid (DMSA) as the active ligand. Upon reconstitution with sterile sodium pertechnetate (99mTc) solution, it forms the technetium (99mTc) succimer complex. Following intravenous injection, the tracer specifically accumulates in the renal cortex, primarily within the cells of the proximal convoluted tubules. This localization allows for high-resolution scintigraphic evaluation of renal morphology, detection of focal cortical abnormalities such as scarring or pyelonephritis, and assessment of relative renal function. It is widely used in pediatric and adult nuclear medicine for detailed kidney evaluation.

Brand names
Mercapton
Other names
99mTc-DMSATechnetium (99mTc) succimerDMSA cold kitdimercaptosuccinic acid kit

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