mercaptopurine

Mercaptopurine is a small molecule antimetabolite and purine antagonist used primarily in the treatment of acute lymphoblastic leukemia (ALL) in both adults and children. It works by inhibiting purine nucleotide synthesis, thereby interfering with DNA and RNA synthesis and function, which leads to the inhibition of cancer cell growth. Its immunosuppressive properties are also notable. The drug is typically administered orally as a tablet or suspension, often as part of combination chemotherapy regimens[1][2][3][4][5].

Brand names

PurinetholPurixanXaluprine

Other names

1,9-dihydro-6H-purine-6-thione6-ThiohypoxanthineMercapurinMercaptopurinumMercaptopurinaMercaleukimPurinethiol