Drug intelligence / Profile preview

Merck cathepsin K compound 23

Development stage
Unknown
Lead developer
Merck
01

Overview

Merck cathepsin K compound 23: sourced facts only. name: "Herein, we report the SAR studies which led to the discovery of the highly selective oxazole compound 23, which was subsequently shown to inhibit cathepsin K in vivo as measured by reduced levels of urinary C-telopeptide of collagen type I in dog." [PMID:35944849]; target: "Herein, we report the SAR studies which led to the discovery of the highly selective oxazole compound 23, which was subsequently shown to inhibit cathepsin K in vivo as measured by reduced levels of urinary C-telopeptide of collagen type I in dog." [PMID:35944849]; developer: "Discovery Chemistry, MRL, Merck & Co., Inc., PO Box 4, West Point, PA 19486, USA. Electronic address: [email protected]." [PMID:35944849]

02

Targets

CTSK (Cathepsin K)

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