Drug intelligence / Profile preview

meriones unguiculatus skin

Development stage
Unknown
Administration
Percutaneous, Intradermal
01

Overview

Meriones unguiculatus skin is a diagnostic allergenic extract derived from the skin or pelt of the Mongolian gerbil (*Meriones unguiculatus*). It is primarily utilized as a diagnostic tool for identifying allergic sensitivities to gerbil dander or skin proteins. The product is typically formulated as a solution for subcutaneous injection or skin prick testing, often at a concentration of 0.05 g/mL. As a diagnostic allergen, it works by eliciting a localized hypersensitivity reaction in sensitized individuals, allowing for the clinical assessment of pet-related allergies. Upon administration, the extract's proteins cross-link allergen-specific IgE antibodies on the surface of mast cells and basophils, triggering the release of histamine and other mediators that produce a visible wheal-and-flare reaction.

Other names
Mongolian gerbil skin extractMeriones unguiculatus skin extract
02

Targets

IgE (Immunoglobulin E)

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