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Meritup
- Development stage
- Preclinical
- Lead developer
- Phytofound Biotech
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Meritup is a standardized botanical formulation developed by Dr. Reddy's Laboratories as an oral solution to alleviate cancer-related fatigue (CRF) in patients undergoing chemotherapy, particularly those with metastatic breast cancer. Classified as an Ayurvedic proprietary medicine or multi-ingredient nutraceutical, its composition includes extracts of various adaptogenic and rejuvenative herbs such as *Withania somnifera* (Ashwagandha), *Asparagus racemosus* (Shatavari), *Glycyrrhiza glabra* (Yashtimadhu), and *Tinospora cordifolia* (Guduchi). The therapeutic effect is attributed to its adaptogenic properties, which help modulate the hypothalamic-pituitary-adrenal (HPA) axis and regulate cortisol levels, alongside anti-inflammatory actions that inhibit pro-inflammatory cytokines like interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α). It is currently under clinical evaluation to assess its potential as a supportive care intervention to improve physical energy and quality of life in oncology patients.
- Brand names
- Meritup
- Other names
- Meritup Oral Solution
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)GR (Glucocorticoid receptor)
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