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**MesemCart** is an investigational allogeneic umbilical cord tissue-derived mesenchymal stromal cell therapy developed by BIONCaRT for focal cartilage defects of the knee. The product is intended for one-time local application to the cartilage defect during minimally invasive or arthroscopic surgery, using a collagen-containing support matrix. It is being evaluated for safety, tolerability, and preliminary efficacy in regeneration of hyaline-like cartilage and improvement of symptoms associated with knee cartilage damage. ([bioncart.com](https://bioncart.com/en/))
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