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mesenchymal stem cells (Cellonis Biotechnologies)

Development stage: Unknown
Lead developer: Cellonis Biotechnologies
Modality: Stem Cell Therapies → Cell Therapies
Administration: Intravenous, Intra-arterial

Overview

Mesenchymal stem cells (MSCs) developed by Cellonis Biotechnology are an autologous cell therapy derived from bone marrow, currently being investigated for the treatment of type 2 diabetes mellitus and associated insulin resistance. The therapeutic protocol involves a multi-step administration process: an initial percutaneous transplantation via the pancreatic artery followed by two subsequent intravenous infusions. These MSCs are hypothesized to exert therapeutic effects through immunomodulation, reduction of systemic inflammation, and potential regeneration or support of pancreatic beta-cell function, thereby improving insulin sensitivity and glycemic control in patients.

Other names: Bone marrow mesenchymal stem cellsBM-MSCsABM-MSCsAutologous bone marrow mesenchymal stem cellsCellonis BM-MSCs

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