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MesoCancerVac
- Development stage
- Phase 1
- Modality
- Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies, Vaccines & Immunotherapeutics
- Administration
- Intravenous, Intradermal
01
Overview
MesoCancerVac is an investigational cancer vaccine therapy that utilizes autologous dendritic cells pulsed with allogeneic tumor cell lysates (fragments of tumor cells). Dendritic cells are potent antigen-presenting cells capable of stimulating antigen-specific T cell responses, thereby promoting anti-tumor immunity. The therapy is being developed for the treatment of pancreatic adenocarcinoma, metastasized pancreatic ductal adenocarcinoma, and peritoneal mesothelioma. It was also previously under development for malignant pleural mesothelioma. The vaccine is administered via intravenous and intradermal routes[9][6].
- Brand names
- MesoCancerVac
- Other names
- MesoCancerVac
02
Targets
pMHC–TCR (Peptide–MHC–T-cell receptor complex)
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