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mesocella-ortho
- Development stage
- Phase 2
- Lead developer
- Jagiellonian University
- Modality
- Mesenchymal Stem Cells → Adult Stem Cells → Stem Cell Therapies → Cell Therapies
- Administration
- Intraarticular
01
Overview
MesoCellA-Ortho is a tissue-engineered advanced therapy medicinal product composed of in vitro expanded autologous human adipose tissue-derived mesenchymal stem/stromal cells (AT-MSCs). The product is designed for intraarticular administration, with each dose containing 20 million AT-MSCs resuspended in a carrier solution. Its primary mechanism involves cell replacement and regenerative effects mediated by the administered autologous AT-MSCs. MesoCellA-Ortho is being developed for the treatment of osteoarthritis, particularly knee osteoarthritis, including patients with comorbidities such as type 2 diabetes and obesity. The therapy aims to improve joint function and reduce pain through the regenerative potential of MSCs[1][3][5].
- Brand names
- mesocella-ortho
- Other names
- MesoCellA-Ortho
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