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Metabolica probiotic combination
- Development stage
- Preclinical
- Lead developer
- Metabolica Health
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
**Metabolica probiotic combination** is an unnamed preclinical natural-health-product candidate developed by Metabolica Health for glucose health and weight management in prediabetes. The proposed approach uses a probiotic mixture to increase endogenous gut production of 4-cresol, a microbial metabolite associated in preclinical research with improved glucose homeostasis, enhanced glucose-stimulated insulin secretion, and support of pancreatic beta-cell function. The individual probiotic strains, dosing, formulation, route of administration, and manufactured product composition have not been publicly disclosed. Metabolica Health publicly highlights research on 4-cresol and metabolic health. ([metabolicahealth.com](https://www.metabolicahealth.com/pages/publications))
- Other names
- Metabolica probiotic combination
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