Drug intelligence / Profile preview

MeTAG

Development stage
Unknown
Lead developer
First Affiliated Hospital of Xi'an Jiaotong University
01

Overview

MeTAG: sourced facts only. name: "Through bridging the methyltransferase PRMT5 proximity to a POI, MeTAG facilitates the arginine methylation of POIs, including known arginine methylated proteins, androgen receptor (AR) and protein kinase B (AKT), as well as a neo-substrate E1A binding protein (p300), in a reversible and PRMT5-dependent manner." [PMID:40487645]; target: "Through bridging the methyltransferase PRMT5 proximity to a POI, MeTAG facilitates the arginine methylation of POIs, including known arginine methylated proteins, androgen receptor (AR) and protein kinase B (AKT), as well as a neo-substrate E1A binding protein (p300), in a reversible and PRMT5-dependent manner." [PMID:40487645]; developer: "Department of Urology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China." [PMID:40487645]

02

Targets

PRMT5 (Protein arginine N-methyltransferase 5)

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