metallic silver

Metallic silver is an elemental substance widely utilized in medical applications for its potent, broad-spectrum antibacterial properties. It is commonly incorporated into medical devices such as wound dressings, central venous catheters, and therapeutic garments, often in the form of silver nanoparticles (AgNPs) or nanostructured coatings. The primary therapeutic effect is mediated by the sustained release of silver ions (Ag+), which exert toxicity against bacteria through multiple mechanisms: disrupting cell wall and membrane integrity, binding to and denaturing essential metabolic enzymes, and interfering with DNA replication. Clinical use focuses on preventing or treating infections in chronic wounds, reducing *Staphylococcus aureus* colonization in atopic dermatitis, and minimizing catheter-related bloodstream infections.

Brand names

Aquacel AgAquacel Ag+ ExtraBinamedOligonActicoatDermaCura

Other names

silversilver nanoparticlesAgNPsnanosilvercolloidal silver