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METamycin (also known as OC136) is an investigational antifungal eye drop formulation developed by Nanomerics for the treatment of fungal keratitis. The drug utilizes Nanomerics' proprietary Molecular Envelope Technology (MET) nanoparticle platform to deliver a small molecule antifungal agent. The MET nanoparticles are designed to improve drug penetration into fungal biofilms and enhance delivery to the cornea, addressing significant unmet needs in fungal keratitis treatment where current therapies are limited by poor bioavailability and frequent dosing requirements. While the specific active ingredient has not been explicitly confirmed by the company, published research suggests it likely utilizes amphotericin B or a similar potent antifungal agent. The program has completed Phase 1 development.
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