Drug intelligence / Profile preview

Metatrol Pro

Development stage
Unknown
Lead developer
American BioSciences
Modality
Small Molecules
Administration
Oral
01

Overview

Metatrol Pro is a super-concentrated dietary supplement containing Fermented Wheat Germ Extract-Super Concentrate (FWGE-SC), developed for supportive care in cancer patients. It is produced through a specialized process that removes gluten and non-active components from standard fermented wheat germ extract, resulting in a more potent formulation that requires a significantly lower dosage than traditional FWGE products. Metatrol Pro works by modulating glucose metabolism in malignant cells, specifically by inhibiting enzymes in the pentose phosphate pathway such as glucose-6-phosphate dehydrogenase (G6PD) and transketolase, which limits the availability of ribose for DNA synthesis. Additionally, it enhances the immune system's anti-tumor response by increasing natural killer (NK) cell activity and downregulating the expression of MHC class I molecules on the surface of cancer cells, thereby improving immune recognition. It is marketed by Indochina Healthcare as a supportive nutritional intervention to support metabolic health and immune function in individuals undergoing cancer treatment.

Brand names
Metatrol ProMetatrol
Other names
FWGE-SCFermented Wheat Germ Extract-Super Concentrate
02

Targets

MHC I (MHC class I})TKT (Transketolase)G6PD (Glucose-6-phosphate dehydrogenase)

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